In the article, the example of medicinal plants shows the possibilities of using wild-growing species of natural flora. The list of families of the Crimean flora with the number of medicinal plants registered in the official pharmacopoeia and widely used in folk medicine is given. The importance of the flora of the Crimea for the availability of useful plant species on a global scale is demonstrated.

The medicinal plants collection (538 taxa) has the same age as Peter the Great Botanic Garden of the Komarov Botanical Institute. For 300 years, the great practice of growing medicinal plants has accumulated here. The collection is unique in quality composition. Here are growing scientific medicine plants of various countries, plants used in homeopathy, in traditional and folk medicine. The most of them are perennial herbaceous plants. For the first time it was determined that 76% of medicinal plants have the highest level of introductory stability. It has been created generic complexes: Paeonia (12 species), Polygonum (10), Iris (10), Rhodiola (9), Salvia (8), etc. Complex research are carried out to identify the signs that are important for the taxonomy of individual species.

An analysis of the current state and prospects for the revival of the industry of medicinal plant growing in Russia is being conducted. It is shown that after approval by the Presidium of the Council under the President of the Russian Federation for Economic Modernization and Innovative Development of Russia in December 2016, the National Technology Initiative (NTI) Roadmap (DC) "HealthNet", one of the significant control results of which is the creation of the industry of medicinal plant growing and production of traditional herbal medicines for various nations of the world, on the initiative of the Association of Producers and Consumers of Traditional Herbal Medicines with the scientific support of the All-Russian Research Institute of Medicinal and Aromatic Plants, within the framework of the project "Restoration of the industry of medicinal plant growing", a year ago began active work to increase of the assortment of cultivated traditional medicinal plants and expand their cultivation in different regions.

In 2016-2017, experiments were conducted at the VILAR to compare the effectiveness of the use of growth stimulators «Ribav-Extra» and «Epin-Extra» and microfertilizers «Citovit» and «Microvit-6 (silicon)» for seedling of the Rhodiola rosea L.) when grown in protected soil. The positive effect of treatments in the combination «Ribav-Extra» + «Epin-Extra» + «Cytovit» and microfertilizer «Microvit-6 (silicon)» on the growth and productivity of plants 2 years of vegetation was revealed.

A primary study of introduction of 14 species of the genus Potentilla L. ( P. alba L., P. argentea L., P. astracanica Jacq., P. aurea L., P. chinensis Ser., P. crantzii (Crantz) Beck ex Fritsch, P. fissa Nutt., P. fragiformis Willd. ex Schltdl., P. kurdica Boiss. & Hohen ex Boiss, P. longifolia Willd. ex Schltdl, P. orientalis Juz., P. recta L., P. salesoviana Stephan, P. tanacetifolia Willd. ex Schltdl.) on the basis of the South-Ural Botanical Garden-Institute of Ufa Federal Research Centre of Russian Academy of Sciences. It was revealed that the seeds of the genus Potentilla are characterized by small size, grayish-orange color, ribbed or retina. As a result of studying the laboratory germination of seeds, it was shown that the first shoots of these species appear on the 4th - 7th day. High rates of laboratory germination and germination energy are distinguished by P. alba , P. argentea , P. fragiformis , P. salesoviana , P. tanacetifolia . The minimum parameters of these parameters were noted in P. chinensis . The weight of 1000 seeds varies from 0,13 g to 0,78 g. According to the analysis of the dynamics of growth in the first year of vegetation, it is possible to distinguish cultivars with different intensity of daily growth in different periods. Species with one, two and three growth peaks are noted.

Data on an introduction of aromatic species of plants from the Lamiaceae Lindl. family are provided in the Cheboksary branch of the Main botanical garden in the Cheboksary branch of the Main botanical garden of N.V. Tsitsin of the Russian Academy of Sciences conditions of the Chuvash Republic. Data on a source of receiving plants, data on fructification, stability, manifolding, number of copies in a collection, a phenology are specified.

The greenhouse collection of VILAR contains 11 species of Myrtaceae family. In article, the description of 7 most interesting species applied in medicine. The short botanical description of species, data on use of these taxa as food and commercial crops are represented. Data on use of these species are also provided in medicine and information on features of growth, development and phenological phases in the greenhouse conditions are represented.

We studied biologic features of new medicinal plant-gypsywort ( Lycopus europaeus L.) under cultivation in Moscow region. Natural recourses of gypsywort cannot provide raw material manufacture of drugs based on gypsywort. The results of study shown that gypsywort normally growth and fruits under cultivation. Comparative analysis of methods of reproduction shown that seedlings from greenhouses provide more harvest than direct seed sowing in the soil. Biological features of plants- the ability to form stolons can be successfully used for vegetative reproduction.

In the course of breeding in VILAR (Moscow region) 2012 - 2016, in self-pollinated progeny of the promising breeding sample was selected and studied a new hereditary morphotype Origanum vulgare L. - prostrate original form. The above-ground part of the plants are height of 10 - 15 cm, consists of more than 300 shoots, does not form a typical branched rhizome and complex paniculate inflorescence. Vegetative buds of renewal are on seasonal shoots in 5 - 7 cm above the soil surface, inside the above-ground part. The content of essential oil in the dry above-ground part is 0,43 - 0,35%.

On the basis of long-term monitoring studies was determined the response of traditional and perspective for cultivation of perennial essential oil crops on the impact of weather-climatic factors under conditions of the Southern coast of the Crimea. A comparative analysis of plant species for variations of terms the phenological stage and the adaptive potential has been estimated. The long-term dynamics is investigated and tendencies of modern changes of the environment factors limiting synthesis and accumulation of essential oil during flowering of plants Thymus vulgaris L., Thymus mastichina L. and Lavandula x intermedia Emeric ex Loisel. are revealed.

The description of species of official plants of flora of North America, the Far East, Siberia and Central Asia used in domestic medicine is presented. The normative documentation regulating quality of raw materials, periods of passing of the main phenological phases, features of reproduction, stability of populations of the presented plants in the conditions of the Botanical garden of VILAR are specified.

The article presents the results of studying the biological features of Ruta graveolens L in growing in the southern coast of the Crimea: the results of phenological observations indicating the duration of the phenological phases of development, the characteristics of flowering and pollination, compared to Ruta graveolens growing in the foothill Crimea. Dynamics of accumulation of essential oils in the above-ground organs is determined, optimum terms of raw material preparation with the greatest accumulation of essential oils are established.

The results of long-term studies of growth, development and productivity of the plantations of the Elsholtzia Stauntonii Benth. In two agro-climatic regions of the Crimea under irrigation conditions are presented. The optimal terms for collecting raw materials after irrigation for obtaining essential oil are determined.

Intraspecific variation of a wide range of economically valuable features of Monarda fistulosa L. and Nepeta transcaucasica Grossh. due to the breeding objectives had been studied. Diversity of seed generation gives the opportunity to use method of individual selection with subsequent clonal fixing of signs to produce new highly productive varieties. Clones of M. fistulosa L. №№ 38-8, 33-9-1, 31-10-3, 30-10-4, 39-8-1, 34-7 and N. transcaucasica Grossh. №№ 19-19, 18-7, 17-1, 21-7, 20-19, 20-6 are of interest for further breeding work.

The collection of aromatic plants of the Donetsk Botanical Garden includes 204 species and intraspecific taxa from 60 genera and 15 species. Our multifunctional approach to the use of aromatic plants implies their demonstration in special display areas in steppe conditions, developments of original plant compositions and functional food supplements, selection of the plant range for agriculture with view of import substitution for laying out of honey plantations and domestic bee-keeping support.

The laboratory studies of germination and seed germination energy of three species of Rhodiola L. showed, that the seeds of R. Kirilowii need a longer period of stratification compared to R. iremelica and R. rosea . For acceleration the germination of Rhodiola seeds, preliminary treatment with solutions of growth stimulants EPIN-extra, Zircon and Ribav-extra was carried out. Application of EPIN-extra improved seed germination up 86, 8% and 90%, respectively in plants of R. rosea and R. iremelica. To increase germination by 23.2% of seeds R. Kirilowii effective use of Zircon bioregulator.

For the first time in the conditions of Krasnodar Krai tests of the retardant of Hardy on a camomile pharmaceutical grades "Situated near Moscow" autumn crops are carried out. Influence of the retardant for productivity of inflorescences, content of essential oil and its structure and also on seed efficiency and quality of seeds was investigated. Hardy's processing was carried out in a phase of the beginning of budding of culture at the consumption rate of medicine of 2 ml/l. Sampling for definition of essential oil was carried out in 8, 10, 12 days after processing. Application of the retardant has exerted insignificant impacts on growth of plants and productivity of inflorescences, but the content of essential oil increased to 43%. Respectively and an exit of essential oil from hectare raised up to 57%. Studying of composition of essential oil of a camomile pharmaceutical has shown increase in his main components: α - bisabolol for the 8th day about 87%, for the 12th day - 62%, chamazulene for the 8th day - 19% have increased; for the 12th day - 17%. Processing of plants a retardant has allowed to increase productivity of seeds to 30%, and the mass of 1000 seeds has increased for 12%.

Data on the mass fraction and component composition of essential oil of 5 species of the genus Mentha L. from the collection of the Nikitsky Botanical Garden are given. A kind of Mentha citrata as the most promising for cultivation on the Southern coast of the Crimea is distinguished by a set of economically valuable signs. The main components of the essential oil are linalool 40.5%, linalyl acetate 20.7%. Essential oil is of interest for the food industry and aromatherapy.

The results of a multi-year introductory study of Scutellaria baicalensis Georgi development peculiarities are presented. in the conditions of the Southern coast of Crimea. It is shown that this Far Eastern species normally develops in conditions of a dry subtropical climate of the Mediterranean type, passes through all phases of ontogeny, forms viable seeds with high germination. Plants are characterized by high productivity of aboveground and underground masses. Medicinal raw materials from the roots of Scutellaria baicalensis are characterized by high antioxidant activity (84.6 ± 5.0 mg GA /g in alcohol extract), and contains a significant amount of polyphenols and flavonoids.

Medicinal plants are growing on the broad areas; there are cosmopolites, endemics, cultural plants. Weeds also have therapeutical properties. Onopordum acanthium L. is used in traditional medicine such as anti-inflammatory, cardiotonic, antitumor plant. In this paper there is a review about geographical location, habitat type, chemical content, pharmaceutical properties. Scotch thistle is a perspective plant in the medicine and pharmacy.

Silaum silaus L. - is of interest for a detailed and in-depth study of the chemical composition and pharmacological activity in view of its wide application in folk medicine, but insufficient knowledge. Pharmacological activities of interest to us, in particular anticancer, may be associated with different groups of BAS. In this paper, the qualitative composition of organic acids, as well as the qualitative and quantitative composition of the sum of carotenoids, has been studied.

The data about qualitative and quantitative composition of biologically active substances (volatile compounds, phenolic substances, vitamins) in water-ethanolic extract of Mentha longifolia L. have been given in the paper. Concentration of volatile compounds in the water-ethanolic extract of horse mint was 974.6 mg/100 g. Using the gas chromatography method the component composition of volatile compounds in the extract was discovered. 20 components have been determined in the extract, 17 - have been identified. The most characteristic volatile compounds for water-ethanolic extract of horse mint specimen were monoterpenes, monoterpene ketones and alcohols. It has been discovered that the main volatile components of extract were menthone (53.2%), isomenthone (27.7%), trans-sabinengidrat (8.2%) and 1,8-cineole (6.2%), whereas the concentration of each of the remaining components does not exceed 1%. The content of phenolic substances in the water-ethanolic extract of horse mint was 3003.3 mg/100 g. Using the high performance liquid chromatography method the component composition of phenolic substances in the extract has been defined. 13 components have been determined in the extract. The extract contains caffeic acid, chlorogenic acid isomers, rosmarinic acid and luteolin glycosides. Among the phenolic substances of horse mint extract rosmarinic acid (50.2%) dominates. The content of ascorbic acid in the test extract was 13.78 mg/100 g and content of carotenoids - 2.34 mg/100 g. Based on retrieved data the conclusion about possibility of use this extract to different types of products with high biological value has been made.

The technology of obtaining tablets with leaf powder, liquid and dry extract from leaves Juglans regia L. has been developed. Methods of standardization of herbal drugs on the content of the amount of naphthoquinones are proposed. The methods are validated by linearity, specificity, accuracy, repeatability, and interoperational accuracy.

The drug of the hedge hyssop (Gratiola officinalis L.) is a pharmacopoeia plant with a number of useful pharmacological effects. However, because of the poor knowledge of the chemical composition, there are no modern medicines based on this plant in the Russian pharmaceutical market. One of the significant indicators of the authenticity of medicinal plant raw materials is the absorption spectra characteristic of the extracts based on this plant. In the present work, the results of spectrophotometric studies of water-alcohol extracts from the herb of the drug of hedge hyssop are presented. Localization сcharacteristics of phenolic compounds in the herb were revealed, quantitative characteristics of the content of total flavonoids and phenylpropanoids were calculated.

The fruits from plants of tribe Menthae Lamiaceae family biology collection of All-Russian Research Institute of Medicinal and Aromatic Plants (Moscow region) were studied. The fruits of Dracocephalum moldavica; Melissa officinalis; Origanum vulgare; Salvia officinalis as valuable seeding material have been investigated. Their yield from the fruit heap was determined, the seeding material dispersed analysis was carried out and the mass of 1000 fruits was calculated.

The Mikhaylovka city in the Volgograd region is understudied in mycological position. The research was conducted in 2016 and 2017. With the help of the literature data analysis, it was possible to find out that of the 70 mushrooms species found in this territory, 34 are medicinal. The article is reported an annotated list of mushrooms species indicating the substrate, the frequency of occurrence, the harvest date (for a single finding), the collection number in the fungarium of the Volgograd State University (VOLSU), biologically active substances.

The content of the total flavonoids in the fruits and bloomy shoots of some hawthorn species has been studied. It was found that the content of total flavonoids in fruits of various species of hawthorn are significantly inferior to those in shoots of similar species.

In the paper, the actuality and perspectivity of the using of the herb of the Monarda fistulosa of the labiate family ( Lamiaceae ) is substantiated as a perspective type of medicinal plant raw material for obtaining of the medicinal preparations with antimicrobial and anti-inflammatory activities. As a result of the study, the essential oil of the Monarda fistulosa, which was grown on the territory of the Samara region, was obtained and received a quantitative assessment (Method 1, Monograph 1.5.3.0010.15 (The State Pharmacopoeia of the Russian Federation XIII edition). The content of essential oil calculated on air-dry raw materials was 1, 67%. The component composition of the essential oil was determined by the GLC method with mass-selective detection. There were identified 16 components, of which are the carvacrol (46,34%), the β-cymene (30,97%), the thymol (1,17%) are dominated by the peak area.

The article gives an analysis of the literature data on the use of the Satureamonta na L. in the food industry. The data on the quality of raw materials and essential oil derived from the Nikitsky Botanical Garden of the Satureamontana cultivar KrymskiyIzumrud allowing to use it for the production of biologically active additives are presented.

The article presents new approaches to the standardization of the reproduced drugs (MP): "Ivy leaves extract, cough syrup", "Ginkgo biloba extract dry, substance", "Sinusol, tablets", "Cough syrup with plantain lanceolate", " extract, coated tablets, 0.5 mg. " Methods of standardization reflecting an individual approach to each drug are proposed and consist of a combination of various physicochemical methods: photometric (UV spectrophotometry), chromatographic (high-performance chromatography (HPLC)) and microscopic. Methods for the quantitative determination of individual compounds (aucubine, colchamine, colchicine, quercetine, kaempferol, isoramnetine) are described using HPLC. Presented is a microscopic analysis of the herb sorrel (Rumex acetosa Linne) and spring primrose flowers (Primula veris Linne).

The present work reports the results of research on wild and cultivated plants having diuretic and litholytic action in the conditions of growing in the North Caucasus. The objects of research were taken to be the following four species: Agrimonia eupatoria L., Rosa canina L., Potentilla alba L. and Helianthus annuus L. Each object is given phytochemical characteristics in the paper which presents the techniques for extraction and identification of the bioactive compounds: phenol and polyphenol substances, organic acids, sugars and polysaccharides.

The study of phenolic acids in the leaves of rosemary (Rosmarinus officinalis L.) white from the collection of Nikitsky Botanical garden. Chromatographic studies of alcohol-water extracts from raw materials showed the presence of rosemary, ferulic, coffee, cinnamon acids. The content of the major component - rosemary acid was established by capillary electrophoresis method. Spectrophotometrically, the content of amount of phenolic acids in terms of rosemary acid, which was 3.69±0.12%, was studied in the alcohol-water extracts.

The results of physical and chemical analysis of the properties of flaxseed oil with the addition of bifunctional and heteronuclear coordination compounds. As for the solvent and heteronuclearbifunctional coordination compounds used ethanol as additives were used biologically active substances complex iron (II), (III) with aspartic acid

The comparative elemental composition of the fruits of Lycium barbarum L. introduced in the Botanic garden of Vladikavkaz (North Ossetia-Alania), of Lycium barbarum (commercially available samples), and of wild Lycium ruthenicum Murr. collected in the Absheron district of the Tugchay river was investigated. A high content of trace elements including essential ones was found in the fruit of the samples studied. Major in the fruit of the introduced Lycium barbarum was magnesium - 468.5 mg / kg; in the commercially available Lycium barbarum - silicon (546.25 mg / kg); in the Lycium ruthenicum - iron (870.7 mg / kg), silicon (681.5 mg / kg), magnesium (547 mg / kg). Molybdenum (2.68 mg / kg) and tin (0.7 m g / kg), were found in the fruits of the Lycium barbarum (introduced sampl), but they were not found in the other two samples. The maximum content of lead in all three samples does not exceed acceptable standards.

The genus Eryngium L. belongs to the subfamily Saniculoideae sem. Apiaceae, Eryngium caucasicum Trautv. and Eryngium planum L. - perennial herbaceous plants up to 70-90 cm high. Distributed by sycophants in the Caucasus, Western Siberia and the European part of Russia, as well as in Central Asia. They grow in pastures, fallow lands, in the outskirts of fields, at the edges of forests, sometimes as weeds. As a result of the conducted studies, the quantitative content of water-soluble polysaccharides, pectin substances, hemicellulose A and hemicellulose B in the roots of a blue-eyed flat-leafed and blue-hued Caucasian blossom was determined. It was found that the roots of Eryngium planum contain 2 times more polysaccharides than the roots of Eryngium caucasicum. The results obtained show us the prospect of further investigation of the polysaccharide complex of these plants.

In the article T.F. Golubova and V.N. Lyubchik, the dynamics of indices of vegetative regulation based on the data of the spectral analysis of the heart rhythm, features of aerobic metabolism according to veloergometry and psychoemotional tone (according to the SAN test) in 98 children with recurrent bronchitis under the influence of the sanatorium- resort treatment, which included aerophytotherapy with essential oils of plants, in the conditions of Evpatoria resort.

The results of the long-term researches of phytoncide and medicinal woody plants of the collection of the arboretum of the VNIISPK gene pool are presented. The analysis of the state and evaluation of the decorativeness of the research objects for the subsequent working out of health-improving routes and resting places on the territory of the arboretum are presented. We have revealed the species and accessions which are in excellent condition, have high resistance to pests and diseases and have a high degree of the evaluation of decorativeness. Routes and resting areas should be located near the woody plants that have a complex of environment-forming properties to ensure the optimal health effect.

Aroma garden roses can be used not only for decorative purposes, but also as a part of the aromaphytotherapeutic areas. Under the conditions of subtropical climate of the Southern Coast of the Crimea cultivars of the garden group of climbing roses are promising for use in different options of wall gardening. As a result of a long term study the collection of garden roses of the Nikitsky Botanical Gardens and the assessment of aroma of the climbing roses cultivars 14 the most fragrant cultivars have been identified. These cultivars are recommended for cultivation in parks and recreation areas, as well as for the arrangement of aromatherapy rosaries.

The effect of water infusion of phytocompositions on subjective sleep characteristics and cardiovascular parameters of 23 elderly women was studied. A significant improvement in the basic parameters of sleep quality 21 days after the use of aqueous phytocomposition has been revealed, as well as stabilization of blood pressure indicators. The investigated phytocomposition "Dream" can be proposed as a means for correction of sleep disorders and in the complex therapy of hypertensive disease in the elderly.

The influence of water infusion of phytocompositions from wild and cultivated plants of the Crimea on the psychoemotional state, as well as on the parameters of hemodynamics and the autonomic nervous system of 23 elderly women has been studied. Application of phytocompositions for 21 days contributed to a significant decrease in anxiety, a tendency to decrease the stroke volume of the heart and achieve an equilibrium state of the autonomic nervous system.

The species of aromatic plants of the park zones of the cities of Abkhazia, which at the moment are represented by 54 taxons, are identified. Tree and shrub plants are represented by 36 taxa, herbaceous flower-decorative - 18 taxa. The phenorhytes of plant development have been studied and their estimation based on the intensity of the smell has been carried out. The periods of the greatest aromatic effect of the investigated plants are revealed. The obtained data will make it possible to scientifically justify the assortment for aromatic medicinal gardens for sanatorium and resort complexes of Abkhazia taking into account the continuous (year-round, changing from one plant to another) aromatic effect.

The aroma for 98 varieties of tea-hybrid roses of the Nikitsky Botanical Garden collection was evaluated. 42 varieties with intense aroma, sensible at some distance from the flower and 35 fragrant varieties, whose smell are felt in the immediate vicinity of the flower, are revealed. The assessment was carried out and 23 varieties with an intense aroma, suitable for cultivation in the form of a stem, were identified. A range of fragrant tea-hybrid roses was created, including 77 varieties recommended for aromatherapy rosaries. A project of aromatherapy rosary was created and presented.

The influence of EM of long-leaved varieties "Oksamitova" on the psychoemotional state and mental performance of students during training sessions was studied. It is shown that the EM of mint varieties "Oksamitova" had a euphoric and relaxing effect, as well as distinctly manifested effects of workability in the first stage from 8.00 to 9.00 and accumulation of fatigue to the second stage from 11.00 to 12.00 in the morning.

A study was made of the effect of lavender essential oil (EM) on the function of the nervous system in people of different ages. In young people (20-25 years old), the lavender EME increases the speed of simple mental and neuro-motor. In middle-aged people (30-55 years), the lavender EM also increases the speed of simple mental and neuro-motor processes, but the number of errors in the proof-reading sample increases. In elderly people (60-85 years of age) the speed of simple mental work under the influence of lavender EM lime does not increase. Only the number of errors is increased. The effectiveness of the test for complex mental work after aromapsychorelaxation is even reduced.

Essential oil (EM) of mint of long-leaved variety "Oksamitova", containing more than 90% of linalool, renders elderly people mostly stable euphoric action. This manifests itself both in terms of anxiety and depression, and in self-evaluation of the psychoemotional state of the subjects. On the mental performance of EM mint dlinolistnoy grade Oksamitova had a weak effect. On the cardiovascular system (SSS), this EM affected positively, reducing the tension of the CCC.

A comparative study of the effects of essential oils (EO) Peppermint different chemotypes of 1 mg / m3 concentration at different periods of exposure (10 to 30 minutes). It was found that the EM-menthol-menthone mentilatsetatnogo ( "Prilutskaya" variety) menthol-menthone-isomenthone ( "Udaychanka" variety) chemotypes in all terms of improved psycho-emotional state and optimize the function of the cardiovascular system of the elderly. EM-menthone-menthol pulegonovogo ( "Ukrainian" grade) chemotype has a positive influence on the psycho-emotional state and function of the cardiovascular system to a much lesser degree and with a substantial delay. The thought processes improve only the EM of menthol-menton-mentyl acetate chemotypes and only simple ones.