Monitoring studies of changes in the alien fraction of the spontaneous flora of Donbass over a 40-year period showed an increase in the degree of its adventitization from 14% (256 species) in 1985 to 23.5% (548 species) in 2025. This process has intensified in recent decades. This is likely due to the aridization of the climate, as well as the active and poorly controlled import of ornamental plants and other cargo into the country. The families Asteraceae, Poaceae, Brassicaceae, Chenopodiaceae, Fabaceae, Rosaceae, Lamiaceae, Solanaceae, Apiaceae, Amaranthaceae are leading in the systematic structure of the alien fraction of the Donbass flora, which occupy the same positions in the flora of other arid territories of Eurasia. In the range of life forms, more than half of the species are annuals (54.8 %). By origin, the species of the Mediterranean-Iranian-Turanian primary range geoelement predominate – 39.9 %, and by the method of import dominating are xenophytes (60%) andergasiophygophytes (20 %). 16 transformer species from agriophyte group pose the greatest invasive threat.